Bioprocess Intelligence

Predict productioneconomics beforeyou build

Physics-informed AI that predicts your COGS/kg, titer, rate, and yield from as few as 5 lab runs. No more failed scale-ups.

5
Lab runs needed
<30s
Per prediction
6
Organisms
9
DSP operations
01
The Challenge

Scale-up is biotech's most expensive blind spot

The jump from lab to production changes everything—fluid dynamics, heat transfer, mass transport, cellular stress. Empirical data alone can't predict what happens next.

Traditional approaches require hundreds of runs and months of pilot work. Most companies discover their true COGS after they've already committed the capital.

60–80%
of production cost is in downstream processing—yet it's rarely modeled before scale-up
02
The Platform

From lab bench to production floor

One platform that connects your lab data to production-scale economics, with physics-informed predictions at every step.

Physics-Informed Prediction

Neural networks constrained by mass balance, transport equations, and Monod kinetics. Not black-box ML—five lab runs is enough.

Integrated Economics

Every simulation outputs COGS/kg with confidence intervals and sensitivity analysis. Know your cost levers across USP and DSP.

Scale-Up Intelligence

Hydrodynamic modeling for kLa, mixing time, tip speed, and dissolved oxygen at production scale. Know risks before committing capital.

Full DSP Pipeline

Nine unit operations — including foam fractionation for biosurfactants — with organism-specific templates. Captures the 60–80% of production cost that most tools ignore.

Any Organism, Including Yours

Built-in profiles for seven common organisms plus a Custom flow for novel or engineered strains. Bring your own kinetics — or let the model learn them from your lab data.

Supported Organisms

P. putidaS. bombicolaM. aphidisS. cerevisiaePichia pastorisE. coliCHOCustom / Novel strain
03
Who It's For

Built for teams that scale bioprocesses

Whether you're developing a monoclonal antibody, optimizing microbial fermentation, or evaluating a novel expression system, Augur fits your workflow.

Process Development Scientists

Challenge: Spending months on pilot-scale campaigns to discover true production economics

With Augur: Predict COGS/kg from bench-scale data before committing to expensive pilot runs

Bioprocess Engineers

Challenge: Manually calculating scale-up parameters with spreadsheets and rules of thumb

With Augur: Physics-informed modeling of kLa, mixing, DO, and cellular stress at any scale

Techno-Economic Analysts

Challenge: Building COGS models disconnected from actual fermentation performance

With Augur: Integrated USP-DSP economics tied directly to predicted titer, rate, and yield

CMC & Manufacturing Leaders

Challenge: Making capital allocation decisions based on incomplete process understanding

With Augur: Scenario comparison with confidence intervals and sensitivity analysis

04
How It Works

Three steps to production-scale insight

01

Upload Lab Data

Drop CSV files from your fermentation runs. Augur auto-detects columns, handles encoding issues, and scores data quality before you proceed.

02

Configure Scale-Up

Set your production parameters—bioreactor volume, organism, DSP train. Start from organism-specific defaults or customize everything.

03

Get Predictions

In under 30 seconds: production-scale COGS/kg, titer, rate, yield—with confidence intervals, risk factors, and sensitivity analysis.

05
The Science

Built on physics. Not just data.

Traditional ML needs hundreds of runs. Augur's physics-informed architecture embeds conservation laws directly into the model, enabling accurate predictions from minimal experimental data.

Physics-Informed Neural Networks

Conservation laws and transport equations as neural network constraints. The model cannot violate mass balance or energy balance.

ODE Kinetics Modeling

Monod kinetics with product inhibition, overflow metabolism, and Arrhenius temperature dependence. First principles, not curve fitting.

Integrated Process Economics

USP through DSP cost modeling with Monte Carlo uncertainty quantification. Every prediction includes production economics.

06
Why Physics-Informed AI

Not another black-box. Physics you can trust.

Augur's physics-informed neural networks embed conservation laws, Monod kinetics, and transport equations directly into the model architecture. The result: predictions that obey the laws of physics, from 10× less data than pure ML approaches.

Approach
Limitation
With Augur
Traditional CFD
Hours to days per simulation, requires deep expertise
Seconds per prediction, accessible to process scientists
Pure Machine Learning
Needs hundreds of runs, no physical guarantees
5 lab runs, physics constraints prevent impossible predictions
Spreadsheet Models
Static assumptions, no uncertainty quantification
Dynamic predictions with Monte Carlo confidence intervals
Pilot-Scale Testing
Months of time, millions in capital at risk
Virtual scale-up in seconds, de-risk before committing capital

Ready to predict
at scale?

De-risk your scale-up decisions. Know your production economics before you build.