MethodologyScale-upTechno-economic analysis
From 5 lab runs to production-scale COGS: how Augur's prediction pipeline works
The four-stage pipeline behind a 30-second scale-up prediction.
•10 min
AUGUR RESEARCH
Case studies, methodology, and the maths behind physics-informed bioprocess prediction
Deep-dives into how Augur predicts production-scale titer, yield, and COGS from 5–10 lab runs — organism by organism, DSP by DSP, paper by paper.
DSP optimizationTechno-economic analysisMethodology
Why your DSP assumptions drive 60-80% of fermentation COGS
Fermentation is the sexy part. Downstream is where the money goes.
•9 min
Custom organismMethodologyScale-up
Predicting scale-up for a novel strain: the Custom Organism flow
If your strain isn't in the list, you don't need a custom integration.
•7 min
MethodologyScale-up
5 sensor failure modes that silently break your bioprocess predictions
Your prediction is only as good as the sensors that generated the data.
•8 min
S. bombicolaSophorolipidScale-up
Sophorolipid production in S. bombicola: scale-up economics from lab to 50,000 L
Why sophorolipids are the biosurfactant everyone is trying to make work.
•10 min
P. putidaRhamnolipidScale-up
Rhamnolipid production in P. putida: 20,000 L scale-up and COGS
The non-pathogenic rhamnolipid host and why foam fractionation changes the math.
•9 min
Foam fractionationDSP optimizationRhamnolipid
Foam fractionation as primary DSP for biosurfactants: economics and design
Stop fighting the foam. Harvest it.
•8 min
Waste oilFeedstock switchingTechno-economic analysis
Waste cooking oil as a biosurfactant feedstock: COGS impact and operational tradeoffs
Cheap feedstock is the last 20% of COGS work that most producers skip.
•7 min
SophorolipidRhamnolipidMEL
MEL vs sophorolipid vs rhamnolipid: which glycolipid fits which application
Three glycolipid categories. Three very different economic realities.
•9 min
M. aphidisMELSolvent extraction
Predicting industrial MEL production from 6 lab fermentations (Beck et al. 2022)
Six lab runs. 20,000 L scale-up. 35.98 g/L predicted titer — inside the industry band.
•11 min